Containers for medicinal liquids



Weak-v March 12, 1963 Filed -Aug., 1 3, 1958 S. TAUSCHINSKI ETALCONTAINERS FOR MEDICINAL LIQUIDS 4 Shee ts-Sheet l /NvE N TOR S 6 TEPHEN7740.5 LH/ NS KI FELIX W0 YRS CH ATI'ORNE) March 12, 1963 s. TAUSCHINSKIETAL CONTAINERS FOR MEDICINAL LIQUIDS 4 Sheets-Sheet 2 Filed Aug. 13,1958 INVENTORS STEPHEN 7205 c nvs March 12,'l9 63 s. TAUSCHINSKI ETAL 3,CONTAINERS FOR MEDICINAL LIQUIDS Filed Aug. 13, 1958 4 Sheets-Sheet 3lNVENTOR STEPHEN 77HJSCHI SKI FELIX WOYRJCH ATTORNEY s. TAUSCHINSKI ETAL3,081,002

- CONTAINERS FOR MEDICINAL LIQUIDS March 12, 1963 4 Sheets-Sheet 4 FiledAug. 13, 1958 FELIX WOYRSCH Br fizz/ A R EY United States PatentOfiFice3,081,002 Patented Mar. 12, 1963 The invention relates to containers forreceiving and dispensing medicinal liquids, especially infusion andtransfusion solutions. The containers are made from pliable material,preferably synthetic substances such as polyethylene.

According to the invention, the end of the container provided with aneye can be pushed in to form a hollow, the extent to which it can bepushed in being limited by a rib (bead) or channel formed on or in thewall of the container. By pushing in the end of the container, an edgeis formed on the wall of the container which enables the container to bestood up like a bottle. In addition the invention presents the advantagethat by pulling out the pushed in portion of the container, additionalvolume can be obtained which enables other medicaments tobe introducedinto the filled container.

It has been found that it is advisable to make the compressible bottomof the container slightly smaller in cross-section than thecross-section of the container itself, and to divide it into severalrings by concentrically arranged ribs or channels. This measurefacilitates the pushing in of the bottom of the container and results inthat the container, even after its bottom has been pushed in, has acircumferential surface free from folds.

According to another feature of the invention, a closing device isprovided which enables the container to be connected up with an infusionapparatus without auxiliary means.

Several embodiments of the invention are illustrated diagrammatically byway of example in the accompanying drawings, in which FIGS. 1 to 6. showtwo forms of construction of the container according to the invention,

FIG. 1 being an elevation of a cylindrical container,

' FIG. 2 a longitudinal section of FIG. 1, and

FIG. 3 an elevation showing the container in compressed state withbulged end in, position for use;

FIG. 4 is an elevation of a flat container,

FIG. 5 a longitudinal section of FIG. 4, and FIG. 6 an elevation showingthe flat container in compressed state with bulged end in position foruse;

FIGS. 7 to 11 show two further forms of construction of the containeraccording to the invention,

FIG. 7 being an elevation of acontainer provided with ribs and channels,

FIG. 8 a longitudinal section of FIG.. 7, and

FIG. 9 an elevation of the container in collapsed state;

FIG. 10 is an elevation of a container with lengthened lower part, and

FIG. 11 a longitudinal section of FIG. 10 with the bottom pushed in; v I

FIGS; 12 to 17 show a closing device for the container, FIG. 12 being anelevation of a container fitted with such a closing device,

FIG. 13 a plan view of a profiled disc forming part of the closingdevice,

FIG. 14 a perspective view of FIG. 13,

FIG. 15 a sectional view showing the disc in position on the mouth ofthe tubular connection piece of the container,

FIG. 16 a perspective view of a cap forming part of the closing device,and

lated by the concentric beads FIG. 17 is a perspective view of a closingcap of modified construction.

In the embodiments of the invention illustrated in FIGURES 1 to '6 thecontainer a pressed in at one end has an inwardly bulged bottom surfaceor wall 12 forming a hollow cavity, which surface is off-set in relationto the wall of the container by means of a lip (bead) c. The containerin this state is fully filled. It is provided at its other end with atubular connection piece at made in one piece with the container itself.In the middle of the hollow cavity e a projecting member having an eye fis fixed on the bottom surface or wall [2 of the container. Thecontainer can be stood upright for storage. As previously noted, FIGURES1, 2 and 3 illustrate a cylindrical container, while FIGURES 4, 5 and 6show a flat container.

When taking into use, the upright container is opened by cutting off oropening the tubular connection piece d. The infusion apparatus isconnected with :tight fit to the opened connection piece in knownmanner. The pressed in end of the container is then pulled outwards bygripping the eye f. When in use, the container is hung up by means ofthis eye 1.

The bulge formed by the previously pressed in end of the container givesthe container additional volume which enables other medicaments to beintroduced (injected).

In the examples illustrated in FIGS. 7 to 11, the filled container a isprovided at the top with a tubular connection piece a. which is locatedon the upper part g of the container. Adjoining the container par-t g atransverse channel it is formed in the wall of thecontainer. Ribs i arealso provided in the part g and arranged as shown in FIG. 7. In themiddle portion of the container a two diametrically oppositelongitudinal ribs k are formed on the wall of the container. The lowerpart I of the container is off-set by means of a transverse channel Inin the container wall and provided with ribs 11 arranged as shown inFIG. 7. The bottom b of the container can be pressed in or inwardlyinverted and carries on its outer side an eye 1 serving as handle.

The cross-section of the bottom b is smaller than the cross-section ofthe container proper. At the lower end of the container part I thecontainer wall is divided into rings towards the bottom b byconcentrically arranged beads c, 0 (FIG. 7). When the bottom b ispressed in, the beads 0 are located one above the other in reversedorder. The bead c forms the edge on which the container can stand (FIG.8).

The container intended for accommodating infusion solutions, is, as awhole, constructed so that it complies with the requirements laid downfor storing such solutions in glass bottles and is suitable both fordispensing the contents and also for receiving additional medicinalsolutions. For the latter purpose the bottom of the container, when thecontainer is filled, is inwardly inverted and can be bulged out byexerting pressure on the wall of the container. As a result additionalvolume is produeed which enables other medicaments to be added to thesolution already in the container.

The pressing out of the bottom of the container is regu- 0 in such amanner that the wall is turned inside out in outward directionsuccessively from ring to ring.

The channels 11, m and ribs k, i, it formed in or on the container wallenable the containerto collapse almost completely when removing thecontents, because the container wall folds up at the placespredetermined by the arrangement of the ribs and channels (FIG. 9).

In the form of construction illustrated in side elevation in FIG. 10 andin longitudinal section in FIG. 11, the lower part I of the container issomewhat lengthened, the transverse ribs n are replaced by grooves 12and the longitudinal ribs k are continued in the container part I aselements q. The channels r are inwardly directed (FIG. so that, when thebottom b is pressed in, they appear as outer edges (FIG. 11). In thisconstruction the invention of the bottom of the container is facilitatedand the container folds up better.

In FIGS. 12 to 17 a closing device for the containers according to theinvention is illustrated and also constitutes part of the invention.FIG. 12 shows in side elevation a container equipped with such a closingdevice.

The container a made from polyethylene, polyvinylchloride or some othersynthetic substance and can be stood on its pressed-in bottom, has atubular connection piece d which is knurled at s to facilitate handlingwhen inserting the infusion apparatus to be used. The closing device isformed by a profiled disc made from the same material as the containerand its connection piece, and a metal cap made, for example fromaluminium.

The profiled disc t has a hollow beaded edge u and a lower-lying innersurface v which constitutes the pierceable diaphragm of the closingdevice. This disc is slipped on to the edge of the mouth of theconnection piece d. Thus the profiled disc fitting tightly, embraces theupper end of the connection piece d, the annular groove formed by thebeaded edge u in the body of the disc receives the edge of the mouth ofthe connection piece d and the surface v of the disc enters the mouth ofthe connection piece d (FIG.

The cap x made from soft metal (aluminium) and provided with a pull-offtab w is placed on the beaded edge u of the disc 2 and heated accordingto a known process.

Under the action of the heat, the profiled disc t or rather its beadededge u is, on the one hand, Welded to the edge of the mouth of theconnection piece d and, on the other hand, rigidly connected with thecap without the surface v of the disc undergoing any change whatever orbeing in any way affected. In this manner a bacteriaproof convering ofthe surface v is produced.

After the sealing of the container, sterilization is carried out underheat. Germs can then no longer get into the closing device andparticularly not to the surface v thereof. When taking the vessel intouse, the metal cap x is removed with the aid of the pull-off tab w andthe exposed surface v of the disc t pierced by the puncturing pin of theinfusion apparatus.

In the form of construction of the closing device illustrated in FIG.17, small holes y are provided in the circumferential surface of the capx, through which holes the plastic, becoming soft during the welding ofthe profiled disc t on to the connection piece d, can pass so that, oncooling, the metal cap has a particularly firm hold on the profileddisc.

We claim:

1. A container for medicinal liquids formed of plastic material andcomprising a tubular wall and two end wall portions integral with saidtubular wall, a tubular connection member adapted to serve as an outletfor said container, said connection member projecting outwardly from oneof said two end wall portions and including closure means therefor, theother of said two end wall portions including a bottom wall of lesserdiameter than said tubular wall having an eye member extending outwardlytherefrom, said other of said two end wall portions further including acollapsible portion formed therein joining said tubular wall and saidbottom wall, said collapsible portion including means for facilitatingthe collapse of said portion, said means comprising a series of coaxialcircular bead members, said bead members forming therebetween a seriesof coaxial rings having different diameters, said series being formed bya progressive arrangement of said circular bead members in accordancewith the size of their diameters axially of said container from saidtubular wall to said bottom wall, one of said bead members beingdisposed at the junction of said tubular wall and said other of said twoend wall portions, said collapsible portion having a portion of lesserdiameter than the diameter of said tubular Wall, said bottom wall andsaid collapsible portion being so constructed and arranged as to bereceived within said tubular wall upon the occurrence of pressureexerted upon said bottom wall through said eye members, and said one ofsaid head members forming a bottom edge for said container on saidbottom wall and said collapsible portion are received within saidtubular wall, and ribs carried by said tubular Wall for determiningfolding of the container upon emptying thereof.

2. A container for medicinal liquids formed of plastic material andcomprising a tubular wall and two end wall portions integral with saidtubular wall and formed of the same material as said tubular Wall, saidtubular wall including means for determining the folding of thecontainer upon the emptying thereof, said means comprising ribs carriedby said tubular wall, a tubular connection member adapted to serve asthe outlet for said container having a closure means, said tubularmember projecting from one of said two end wall portions, the other ofsaid two end wall portions including a bottom wall having thereon aprojection, said other of said two end wall portions having formedtherein a collapsible portion joining said tubular wall and said bottomwall, said collapsible portion including a portion of lesser diameterthan the diameter of said tubular wall and means for facilitating thecollapse of said collapsible portion, said means for facilitating thecollapse of said portion comprising a series of coaxialccircular beadmembers formed in said other end wall portion, said bead members formingtherebetween a series of coaxial rings in said other end wall portionarranged axially of said container between said tubular wall and saidbottom wall, said bottom wall being of lesser diameter than the diameterof said tubular wall, said bottom wall and said collapsible portionbeing received within said tubular wall upon the occurrence of pressureexerted upon said bottom wall through said projection, the edge of saidtubular wall formed when the collapsible portion is received within thetubular wall forming a bottom edge for the container when said portionis received within the tubular wall. I

3. A container according to claim 2, wherein one of said bead members isdisposed at the junction of said tubular Wall and said other of said twoend wall portions, said one of said bead members forming said bottomedge for said container when said bottom wall and said collapsibleportion are received within said tubular wall.

4. A container according to claim 2, wherein said circular bead membersare of differing diameters, said series comprising a progressivearrangement of said circular bead members in accordance with the sizesof their diameters arranged axially of said container from the junctureof said tubular wall and said other end wall portion.

References Cited in the file of this patent UNITED STATES PATENTS684,986 Higgins Oct. 22, 1901 2,152,862 Bergerioux Apr. 4, 19392,208,744 Bergerioux July 23, 1940 2,623,660 Warren Dec. 30, 19522,661,128 Rieke Dec. 1, 1953 2,661,741 Puckman Dec. 8, 1953 2,758,755Schafier Aug. 14, 1956 2,766,907 Wallace Oct. 16, 1956 2,853,209 McArdleSept. 23, 1958

1. A CONTAINER FOR MEDICINAL LIQUIDS FORMED OF PLASTIC MATERIAL AND COMPRISING A TUBULAR WALL AND TWO END WALL PORTIONS INTEGRAL WITH SAID TUBULAR WALL, A TUBULAR CONNECTION MEMBER ADAPTED TO SERVE AS AN OUTLET FOR SAID CONTAINER, SAID CONNECTION MEMBER PROJECTING OUTWARDLY FROM ONE OF SAID TWO END WALL PORTIONS AND INCLUDING CLOSURE MEANS THEREFOR, THE OTHER OF SAID TWO END WALL PORTIONS INCLUDING A BOTTOM WALL OF LESSER DIAMETER THAN SAID TUBULAR WALL HAVING AN EYE MEMBER EXTENDING OUTWARDLY THEREFROM, SAID OTHER OF SAID TWO END WALL PORTIONS FURTHER INCLUDING A COLLAPSIBLE PORTION FORMED THEREIN JOINING SAID TUBULAR WALL AND SAID BOTTOM WALL, SAID COLLAPSIBLE PORTION INCLUDING MEANS FOR FACILITATING THE COLLAPSE OF SAID PORTION, SAID MEANS COMPRISING A SERIES OF COAXIAL CIRCULAR BEAD MEMBERS, SAID BEAD MEMBERS FORMING THEREBETWEEN A SERIES OF COAXIAL RINGS HAVING DIFFERENT DIAMETERS, SAID SERIES BEING FORMED BY A PROGRESSIVE ARRANGEMENT OF SAID CIRCULAR BEAD MEMBERS IN ACCORDANCE WITH THE SIZE OF THEIR DIAMETERS AXIALLY OF SAID CONTAINER FROM SAID TUBULAR WALL TO SAID BOTTOM WALL, ONE OF SAID BEAD 